Principal component analysis based methods in bioinformatics studies

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Principal component analysis based methods in bioinformatics studies

In analysis of bioinformatics data, a unique challenge arises from the high dimensionality of measurements. Without loss of generality, we use genomic study with gene expression measurements as a representative example but note that analysis techniques discussed in this article are also applicable to other types of bioinformatics studies. Principal component analysis (PCA) is a classic dimensio...

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ژورنال

عنوان ژورنال: Briefings in Bioinformatics

سال: 2011

ISSN: 1467-5463,1477-4054

DOI: 10.1093/bib/bbq090